Metabolic Syndrome definition is a category of risk factors for the likelihood of a person developing Type 2 Diabetes. These factors include sedentary lifestyles, having above average BMI’s, and a family history of Diabetes and heart disease. Likewise, people who have high blood pressure, high blood sugar levels, high cholesterol, or Polycystic Ovarian Syndrome have increased risk for this disease.In addition, a person has the potential to develop heart disease, stroke, and Type 2 Diabetes due to severe damage to the arteries, increased blood clot formation, and improper kidney function as well as nerve, eye, and kidney damage.

Researchers are unsure of the etiology but they know that Hispanics and Asians seem to endure this condition more than other racial groups. In addition, this condition can occur at any age, but increases as people get older.In fact, forty percent of individuals over sixty have the definition of Metabolic Syndrome. Upwards of forty-seven million people,suffer this disease according to the National Heart Lung and Blood Institute. They hypothesize these numbers will climb to match the incidence of obesity and heart disease.

 

Metabolic Syndrome Definition- WHO

 

Depending on the association, the guidelines for determining a Metabolic Syndrome definition vary. The World Health Organization (WHO) published the first documentation on diagnosis criteria, yet their definition is not globally used. They state that patients must meet two of the following criteria in addition to having insulin resistance and the addition of protein in the urine (microalbuminuria) measuring ≥ 20 µg/min.:a BMI over >30 kg/m2, triglycerides ≥150 mg/dL, HDL-C <35 mg/dL in men and <39 mg/dL in women,  and blood pressure ≥140/90 mm Hg.

 

Metabolic Syndrome Definition– NCEP ATP

 

The Metabolic Syndrome definition according to the National Cholesterol Education Program (NCEP) and its report, the Adult Treatment Panel III (ATP), is the most widely used and accepted guideline for diagnosising this condition in the United States. Instead of using BMI, they refer to waist circumference and state that ≥102 cm in men and ≥88 cm in women, triglycerides ≥150 mg/dL,HDL-C <40 mg/dL in men and <50 mg/dL in women, blood pressure ≥130/85 mm Hg, and a Fasting Blood Glucose Test >110 mg/dL (IFG). They do not require presence of insulin resistance or microalbuminuria, but they do need three out of the five above factors met.

 

Metabolic Syndrome Definition –AHA

 

The definition Metabolic Syndrome from the American Heart Association (AHA) and the National Heart Lung and Blood Institute(NHLBI) both use the same criteria, which is a hybrid of criteria from WHO and ATP. They use waist circumference of ≥102 cm in men and ≥88 cm in women, triglycerides ≥150 mg/dL, HDL-C <40 mg/dL in men and <50 mg/dL in women, blood pressure ≥130/85 mm Hg, and a Fasting Blood Glucose Test >100 mg/dL (IFG). They do not require presence of insulin resistance or microalbuminuria, but they do require atypical results of triglycerides, HDL-C, and blood pressure when using medication for treatment.

 

Metabolic Syndrome Definition – IDF

 

The Metabolic Syndrome definition according to the International Diabetes Federation (IDF)states that an individual qualifies for this diagnosis if they are obese, which is defined by waist circumference or a BMI of >30 kg/m2. In addition, they must have two of these factors: triglycerides ≥150 mg/dL, HDL-C <40 mg/dL in men and <50 mg/dL in women, blood pressure ≥130/85 mm Hg, and Fasting Plasma Glucose (FPG)>100 mg/dL or previously diagnosed Type 2 Diabetes.